Radiance Of The Seas Panama Canal Cruise From San Diego - October 4, 2025
16 Night Panama Canal Cruise
Panama Canal one way cruise departs from San Diego on Saturday October 4, 2025. The 16 day cruise ends with the arrival of Radiance Of The Seas in Fort Lauderdale on Monday October 20, 2025.
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Ports of Call
Cabo San Lucas, Mexico
Cabo San Lucas is at the southern tip of the Baja California peninsula. It's a popular resort destination as well as cruise ship port of call.
Mazatlan, Mexico
Mazatlan is a port city on the Pacific coast of Mexico near the mouth of the Gulf of California. Lots of blue water lagoons along the coast, plus the world's highest lighthouse.
Puerto Quetzal, Guatemala
Puerto Quetzal is a port town on the Pacific Ocean coast of Guatemala. Guatemala City, the nation's capital, is about 60 miles inland from here.
Puntarenas, Costa Rica
Puntarenas is a port town on the Gulf of Nicoya on the west side of Costa Rica, about 50 miles west of San Jose.
Colon, Panama
Colon is a port city on the Caribbean end of the Panama Canal. Due to the geographic orientation of Panama, this is actually the west end of the canal.
George Town, Cayman Islands
George Town is the largest city in and the capital of the Cayman Islands. It's on the west coast of the largest island, Grand Cayman, about 450 miles south of Miami.
Departure Port: San Diego Cruise Ship Terminal
Directions: Google Maps - Apple Maps
For the night before your cruise: Hotels near San Diego Cruise Ship Terminal
Wyndham San Diego Bayside
1355 N Harbor Drive
0.2 miles from cruise port
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InterContinental San Diego, an IHG Hotel
901 Bayfront Court
0.2 miles from cruise port
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Hampton Inn San Diego Downtown
1531 Pacific Hwy
0.4 miles from cruise port
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The Guild Hotel, San Diego, a Tribute Portfolio Hotel
500 W Broadway
0.4 miles from cruise port
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Pacific Inn and Suites
1655 Pacific Hwy
0.4 miles from cruise port
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Best Western Plus Bayside Inn
555 W Ash Street
0.4 miles from cruise port
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Residence Inn by Marriott San Diego Downtown
1747 Pacific Hwy
0.5 miles from cruise port
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Hotel Republic San Diego, Autograph Collection
421 W B St
0.5 miles from cruise port
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Top 10 future cruises from San Diego
15 Night Panama Canal
Zuiderdam: Departs on February 27, 2026
20 Night Panoramic Panama Canal San Diego to New York
Insignia: Departs on July 3, 2025
17 Night Panama Canal
Koningsdam: Departs on November 1, 2025
17 Night Panama Canal
Eurodam: Departs on October 9, 2025
18 Night San Diego, California To Fort Lauderdale, Florida
Silver Shadow: Departs on May 9, 2025
14 Night Panama Canal: Mexico and Colombia
Norwegian Jade: Departs on October 18, 2025
13 Night Panama Canal Eastward Cruise
Serenade Of The Seas: Departs on September 19, 2025
25 Night Pacific Coastal and Circle Hawaii Collector
Nieuw Amsterdam: Departs on April 4, 2026
18 Night Baja Peninsula, Mexican Riviera and Pacific Coast
Zaandam: Departs on April 18, 2026
24 Night Wine Country, Pacific Northwest and Circle Hawaii
Koningsdam: Departs on March 29, 2025
More cruises scheduled for Saturday October 4, 2025
22 Night Panama Canal
Eurodam from Seattle
28 Night Westbound Atlantic Ocean Crossing
Royal Clipper from Civitavecchia (Rome)
21 Night Circle Hawaii And California Retreat
Koningsdam from Vancouver
17 Night Circle Hawaii
Koningsdam from Vancouver
23 Night Aegean Vistas Rome to Athens
Marina from Civitavecchia (Rome)
14 Night Flamenco Fascination Lisbon to Rome
Sirena from Lisbon
13 Night Spain, Morocco and Portugal
Royal Clipper from Civitavecchia (Rome)
28 Night Malta, Sicily and Eastern Mediterranean: Asia Minor
Nieuw Statendam from Piraeus (Athens)
12 Night Italy and Ancient Isles Rome to Istanbul
Marina from Civitavecchia (Rome)
11 Night Greek Isles: Santorini, Mykonos and Croatia
Norwegian Pearl from Piraeus (Athens)
Cruise Updates
Equinox from ArgentinaCelebrity Equinox will be spending next December and January making two-week trips out of Buenos Aires to the southern tip of South America and Antarctica
Star Princess Barcelona to Fort Lauderdale
Be aboard as the newest ship in the Princess fleet makes its first cruise across the Atlantic - Halloween included!
Miami Memorial Day Cruises
Cruises out of Miami that include the Memorial Day holiday include parts of world cruises but also a bunch of week-long tours of the Caribbean
Cruises to Iceland
Get ready to escape the summer heat with one of these cruises that include visits to Reykjavik, the capital of Iceland
Sky Princess Cruises
Princess Cruise Line's Sky Princess is currently based in Fort Lauderdale. It'll spend the summer making cruises out of Southampton, England and then from Port Canaveral next winter.
