Grand Princess Panama Canal Cruise From Los Angeles - September 15, 2025
16 Night Panama Canal - Ocean to Ocean
Panama Canal one way cruise departs from Los Angeles on Monday September 15, 2025. The 16 day cruise ends with the arrival of Grand Princess in Fort Lauderdale on Wednesday October 1, 2025.
- Read reviews of Grand Princess
- Check prices on Grand Princess cruises
- Grand Princess deck plans, cabin types, dining options and amenities
- Follow TheCruiseNexus on Facebook for more cruise ideas and information
Ports of Call

Puntarenas, Costa Rica
Puntarenas is a port town on the Gulf of Nicoya on the west side of Costa Rica, about 50 miles west of San Jose.

Panama City, Panama
Panama City is the capital city of Panama with a population of over 450,000. It's on the Pacific coast at the eastern end of the Panama Canal.

Oranjestad, Aruba
Oranjestad is the capital city and primary port on the Caribbean island of Aruba. Just off the northern coast of South America, Aruba is only 20 miles from Venezuela.
Departure Port: World Cruise Center
Directions: Google Maps - Apple Maps
For the night before your cruise: Hotels near World Cruise Center
Sunrise Hotel San Pedro
525 S Harbor Blvd
0.5 miles from cruise port
Compare prices for September 14th
Crowne Plaza Los Angeles Harbor Hotel
601 S Palos Verdes St
0.6 miles from cruise port
Compare prices for September 14th
All Star Inn
411 South Pacific Avenue
0.7 miles from cruise port
Compare prices for September 14th
Best Western Plus San Pedro Hotel & Suites
111 South Gaffey Street
0.9 miles from cruise port
Compare prices for September 14th
Vagabond Inn San Pedro
215 S Gaffey St
0.9 miles from cruise port
Compare prices for September 14th
Americas Best Value Inn Rancho Palos Verdes
29601 South Western Avenue
1.8 miles from cruise port
Compare prices for September 14th
DoubleTree by Hilton San Pedro - Port of Los Angeles
2800 Via Cabrillo Marina
1.9 miles from cruise port
Compare prices for September 14th
Monterey Inn Hotel
233 N. Avalon Blvd
2.0 miles from cruise port
Compare prices for September 14th
Top 10 future cruises from Los Angeles
18 Night World Cruise: Hawaii and French Polynesia
Seabourn Sojourn: Departs on January 6, 2026
19 Night Panama Canal Passage
Seabourn Quest: Departs on April 7, 2026
16 Night Panama Canal - Ocean to Ocean
Island Princess: Departs on February 9, 2026
16 Night Panama Canal - Ocean to Ocean
Coral Princess: Departs on October 28, 2025
16 Night Panama Canal - Ocean to Ocean
Island Princess: Departs on October 22, 2025
16 Night Panama Canal - Ocean to Ocean
Caribbean Princess: Departs on September 30, 2025
27 Night Panama Canal and Caribbean Adventurer
Grand Princess: Departs on September 15, 2025
16 Night Stars and Salsa Los Angeles To Miami
Seven Seas Grandeur: Departs on January 25, 2026
18 Night Panama Canal - Ocean to Ocean
Island Princess: Departs on May 17, 2025
16 Night Panama Canal Eastbound
Celebrity Summit: Departs on September 19, 2025
More cruises scheduled for Monday September 15, 2025
27 Night Panama Canal and Caribbean Adventurer
Grand Princess from Los Angeles
14 Night Italy, The Adriatic and Greece
Viking Vesta from Piraeus (Athens)
21 Night Mediterranean and Adriatic Sojourn
Viking Vesta from Piraeus (Athens)
12 Night Eastern Seaboard Explorer
Viking Mars from Montreal
24 Night Southampton To Lisbon
Silver Dawn from Southampton
16 Night Civitavecchia (Rome) To Barcelona
Silver Ray from Civitavecchia (Rome)
7 Night Venice, The Adriatic and Greece
Viking Vesta from Piraeus (Athens)
9 Night Mediterranean and North Europe From Marseilles
Costa Favolosa from Hamburg
10 Night Mediterranean and North Europe From Genoa
Costa Favolosa from Hamburg
10 Nacht Norwegens Fjorde Mit Geiranger Ab Hamburg
AIDAprima from Hamburg
Cruise Updates
Galveston Christmas CruisesChoose from ten cruises departing from Galveston that will be at sea on Christmas day, from Carnival, Royal Caribbean, MSC and Princess
Updated Norwegian Cruise Schedule
We've updated our database with the Norwegian cruises scheduled through April 2027, including this batch of June 2025 cruises departing from ports all over the planet.
Pre-Thanksgiving in the Caribbean
Holland America's Zuiderdam leaves on November 1st for a week-long tour of the northeastern Caribbean
Great Cruises in August
Our picks for the most interesting cruises departing in August 2025 include a bunch of transatlantic cruises, glacier viewing voyages in Alaska, Scandinavian fjords and Mediterranean tours.
Oceania Insignia from San Diego to New York
There's still time to come along on this 20-night cruise from the US west coast to the US east coast. It's part of Oceania Insignia's 2025 World Tour.
