Norwegian Encore Panama Canal Cruise From San Francisco - October 21, 2025
18 Night Panama Canal: Mexico and Colombia
Panama Canal one way cruise departs from San Francisco on Tuesday October 21, 2025. The 18 day cruise ends with the arrival of Norwegian Encore in Miami on Saturday November 8, 2025. The Halloween holiday (October 31, 2025) is during the cruise.
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Ports of Call

Glacier Bay, Alaska
Glacier Bay National Park and Preserve is 3.3 million acres of mountains, forests, glaciers and fjords. Most cruises to Alaska visit here for views of the glaciers.

Cabo San Lucas, Mexico
Cabo San Lucas is at the southern tip of the Baja California peninsula. It's a popular resort destination as well as cruise ship port of call.

Puerto Vallarta, Mexico
The cruise terminal at Puerto Vallarta is about 25 miles inland from the Pacific Ocean, on the Bahia de Banderas. It's about 1200 miles southeast of Los Angeles.

Acapulco, Mexico
Acapulco is a classic cruise destination on the Pacific Coast of Mexico, about 1600 miles southeast of Los Angeles

Puerto Quetzal, Guatemala
Puerto Quetzal is a port town on the Pacific Ocean coast of Guatemala. Guatemala City, the nation's capital, is about 60 miles inland from here.

Panama City, Panama
Panama City is the capital city of Panama with a population of over 450,000. It's on the Pacific coast at the eastern end of the Panama Canal.
Departure Port: San Francisco Cruise Terminal
Directions: Google Maps - Apple Maps
For the night before your cruise: Hotels near San Francisco Cruise Terminal
Europa Hotel
310 Columbus Avenue
0.6 miles from cruise port
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San Remo Hotel
2237 Mason Street
0.6 miles from cruise port
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Hotel North Beach
935 Kearny Street
0.6 miles from cruise port
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Hotel Zephyr
250 Beach Street
0.6 miles from cruise port
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Hotel Zoe Fisherman's Wharf
425 North Point
0.7 miles from cruise port
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Hotel Riu Plaza Fisherman's Wharf
2500 Mason St
0.7 miles from cruise port
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Wharf Inn
2601 Mason St
0.7 miles from cruise port
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Club Quarters Hotel in San Francisco
424 Clay St
0.7 miles from cruise port
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